A new approach based on bidirectional scanning improves the imaging performance of optoacoustic imaging to quasi-isotropic transverse resolution.
New endoscopic technique provides label-free contrast of tissue
A flexible wide-field endoscope utilising blue excitation light provides label-free contrast of tissue based on fluorescence lifetime imaging of tissue autofluorescence. Fluorescence lifetime imaging (FLIM) of tissue autofluorescence has been shown to provide...
Membranes under observation
Membrane nano-tomography in living cells: Label-free evanescent microscopy enables full-field and real-time tracking of membrane processes.
Measuring skin rejuvenation with two-photon microscopy
In vivo and non-invasive: Collagen remodeling after micro-ablative fractional laser resurfacing can be monitored by two-photon microscopy.
A synergetic pairing: epifluorescent microscopy and electrophoretic microarrays
Detection of nanoparticles and DNA biomarkers at clinically relevant low levels can be achieved by combining epifluorescent microscopy with dielectrophoretic microarrays.
Modeling blood capillaries to prevent shock
Monitoring of blood capillary/vessel patterns with spatially resolved diffuse reflectance spectrometry might allow for the early detection of clinical shock.
Monitoring retina inflammation with Raman spectroscopy
Raman spectroscopy of the retina coupled with multivariate analysis might become a promising tool to study retina diseases in vivo.
SERS probes from silver microneedles get under the skin
Scientists from NTU have suggested the use of metal-coated microneedles to improve below-skin Raman spectroscopy.
Nanoparticle concentration measured acoustically
Three-dimensional optoacoustic tomography enables quantitative measurements of nanoparticle concentrations to evaluate their biodistributions in animal models.
Better quantification of blood samples: more signal, less background
A team based in Germany develop a new method for simultaneous quantification of ZnPP and PPIX in unwashed blood samples.