Knowledge of the processes needed to make precursor cells of eggs and sperm gives insights into reproductive biology and infertility.
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The award-winning Wiley Interdisciplinary Reviews series combines some of the most powerful features of encyclopedic reference works and review journals in an innovative online format.
Water Sharing Across Cultures: Gifts, Exchanges, and other Transfers between Households
Household water sharing is rarely studied by scholars, but is crucial to human survival all around the world.
There and Back Again: Outlier Detection Between Statistical Reasoning And Data Mining Algorithms
Data mining and statistics, the roots and the path of development of statistical outlier detection and of database‐related data mining methods for outlier detection.
Expanding The Gene Expression Repertoire By RNA Recapping
Mammalian cells are capable of recapping mRNAs that have lost their caps.
Glycogen Synthase Kinase-3 and Alternative Splicing
Sequencing of the human genome led to the surprising discovery that we do not have many more protein coding genes than presumably simpler organisms.
Regulation of Cytoplasmic RNA Stability: Lessons from Drosophilia Fruit Fly
The key players within the pathways of RNA decay are well conserved with their mutation or disruption resulting in distinct phenotypes as well as human disease.
Insights Into The Control Of Trypanosome Editing
Specific examples of complex variants, differential effects of editing proteins on the mRNAs within and between T. brucei life stages, and possible control points in the holo-editosomes are examined.
Unconventional RNA-Binding Proteins Step into the Virus–Host Battlefront
Recent proteome‐wide approaches have greatly expanded the census of RNA‐binding proteins, discovering hundreds of proteins that interact with RNA through unconventional RBDs.
Gold Nanoparticles to Probe the Biological Obstacles of Nanomedicine
Despite massive growth in nanomedicine research to date, the field still lacks fundamental understanding of how certain physical and chemical features of a nanoparticle affect its ability to overcome biological obstacles in vivo and reach its intended target.
Keep the Plasmid Party Rolling, But Keep it Cool with Structured Antisense RNAs
Bacterial plasmids constitute a wealth of shared DNA amounting to about 20% of the total prokaryotic pangenome. Plasmids replicate autonomously and control their replication by maintaining a fairly constant number of copies within a given host. Plasmids should acquire a good fitness to their hosts so that they do not constitute a genetic load.