The immunoglobulin G scaffold can be engineered to increase stability, improve efficacy, and allow novel functionality as a potent anti‐cancer therapeutic.
Biosystems
Bee Toxin for Asthma Research
A new delivery system for siRNA targeting lung T cells.
Extracellular RNA in Viral–Host Interactions: Thinking Outside the Cell
Small RNAs and their associated RNA interference (RNAi) pathways underpin diverse mechanisms of gene regulation and genome defense across all three kingdoms of life and are integral to virus–host interactions.
Developmental Origins and Oncogenic Pathways in Malignant Brain Tumors
Brain tumors are among the leading causes of cancer‐related deaths, exhibiting poor prognoses with little improvement in outcomes over the past several decades.
Single-Cell Sequencing of Mitochondrial Mutations Traces Human Cell Lineages
Mitochondrial mutations as cell lineage tracers.
Building Blocks for Biofabricated Models
Special issue in Advanced Healthcare Materials, edited by Jürgen Groll and Jos Malda, covers bioinks, melt electrowriting, printing bone tissue, islet cells, tendons, skin, trachea, kidneys and more.
Who Discovered DNA?
Why do some crucial scientific discoveries get left out of the canon?
Hall of Fame Highlight: Xiaodong Chen
Advanced Materials board member Xiaodong Chen on his scientific and personal motivations.
Writing a Wrong: Coupled RNA Polymerase II Transcription and RNA Quality Control
Processing and maturation of precursor RNA species is coupled to RNA polymerase II transcription. Co‐transcriptional RNA processing helps to ensure efficient and proper capping, splicing, and 3′ end processing of different RNA species to help ensure quality control of the transcriptome.
Cold Atmospheric Plasma Fighting Infections
German researchers tested the efficacy of cold atmospheric plasma in the inactivation and removal of infections.
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