February’s top Advanced Healthcare Materials papers
Disease Prevention
Hydrogels for Immunotherapy
A biomaterial system for immune modulation through expansion of antigen-specific regulatory T cells.
Artificial Cellular Microenvironments
A hybrid platform of microfluidics and nanofibers to reproduce artificial cellular microenvironments with a variety of cellular densities and scaffolds is reported.
Functional microRNA Screen for Organ Morphogenesis
A detailed protocol to assess microRNA function in explanted organs is presented.
A High-Throughput Cell Chemotaxis and Migration Inhibitor Screen
A protocol for a unique high-throughput assay to identify novel small-molecule inhibitors of cell migration.
Two-in-One: A Copolypeptide Provides Antimicrobial Activity and Barrier Properties
A new approach to prevent wound infections: Antimicrobial activities and microbial barrier properties can be designed in a single biopolymer.
Making Insulin Producing Beta Cells by Cell Reprogramming
A robust and reproducible method for “direct programming” of acinar cells into functional beta cells with a polycistronic viral construct and viral transduction of pancreatic tissue in vivo in mice is described.
Featuring Biofabrication, Intraocular Sensors and More: February’s Advanced Healthcare Materials Covers
Research highlights from this month’s Advanced Healthcare Materials issues.
Rapid, Low Cost Detection of E.coli and Shigella
A 16S rRNA targeting oligonucleotide probe to improve target organism specificity and lowers costs for detection of low-level E. coli/Shigella contamination.
Upregulation of Extrasynaptic Inhibitory Receptors Protects against Anorexa nervosa
Results suggest that treatments targeting the activation of specific receptors may be efficacious in preventing the development or relapse of anorexia nervosa.
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