For nearly 35 years, CD4 T-cells and their immunephenotyping and enumeration were the focal points of HIV/AIDS research.
Therapeutics
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Cytometry Part A published ISAC-Cytometry Part A Mentorship Program Special Section: New Developments in Cytometric Phenotyping, Guest Edited by ISAC Marylou Ingram Scholars Kewal Asosingh from Cleveland Clinic, USA, Katarzyna Piwocka from Nencki Institute of...
Multimodal Agent for Cancer Diagnostics and Therapeutics
Chunmeng Shi and co-workers from the Third Military Medical University in Chongqing, China, introduce a small-molecule-based cancer theranostic agent for simultaneous cancer-cell mitochondrial targeting, NIR imaging, and chemo-/PDT/PTT/multimodal therapeutic activities.
Immunity to CRISPR Cas9 and Cas12a Therapeutics
Genome-editing therapeutics introduce foreign nucleic acids and proteins into the circulation and cells, which can activate the innate, cellular, and humoral immunity in human patients. The key obstacle in translating CRISPR therapeutics to the clinic is hence to identify, diminish, and monitor these immunological risks before adverse immune reactions.
From Polymers to Functional Biomaterials
A new special issue in Macromolecular Bioscience highlights emerging applications of polymers for the synthesis of functional biomaterials.
Safe Smiling: Bleaching Teeth Using Plasma Jet
Taiwanese scientists create a new atmospheric-pressure plasma jet tooth bleaching method that is safe, cost effective and portable.
Influenza Antiviral Agent Regulates ROS
Polymeric nanoparticles acting as intracellular ROS regulators show promise as antiviral agents in influenza-infected kidney cells.
Single Cell Transcriptomics of Non-Coding RNAs and their Cell-Specificity
Non-coding RNA expression varies at the single cell level, at least as much variability as protein-coding RNA, and some classes of non-coding RNA may display more single cell variability.
Ancient and Modern Hints: Chemotherapy Resistance in Ovarian Cancer
RNA-binding proteins influence epithelial ovarian cancer progression through complex networks with mRNAs, non-coding RNAs and other proteins.
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