Matrix-metalloprotease (MMP)-sensitive hydrogel particles intend to utilize the unique properties of tumor cells, such as high concentration of MMP enzymes, along with the synergistic activities of an apoptosis-inducing protein (TRAIL) and the TRAIL sensitizer drug Quinacrine.
Magnetic Healing of Brain Injury
Advanced natural multi-functional biomaterials may one day help heal brain injury.
Making Insulin Producing Beta Cells by Cell Reprogramming
A robust and reproducible method for “direct programming” of acinar cells into functional beta cells with a polycistronic viral construct and viral transduction of pancreatic tissue in vivo in mice is described.
Featuring Biofabrication, Intraocular Sensors and More: February’s Advanced Healthcare Materials Covers
Research highlights from this month’s Advanced Healthcare Materials issues.
NO to Multidrug-Resistant Cancer
Photothermal core-shell nanoparticles that can release nitric oxide upon NIR irradiation efficiently reversing multi-drug resistance in cancer.
Gold Nanoparticle-Mediated Photothermal Therapy: Applications and Opportunities for Multimodal Cancer Treatment
Photothermal therapy that uses gold nanoparticles to convert light to heat is effective against cancer both alone and combined with other therapeutic strategies is reviewed.
Your Most Read Includes Hemocompatibility and 3D Bioprinting: January’s Top Advanced Healthcare Materials Papers
This month’s Advanced Healthcare Materials papers you have downloaded and read the most.
Ocular Drug Delivery Powered by Your Body
Researchers from Singapore, China and USA have recently reported in Advanced Materials the first example of a TENG-based self-powered iDDS, and demonstrate its functionality in ocular drug delivery.
Are MoS2 Nanosheets Safe for Use in Humans?
Biodegradability and biocompatibility studies show minimal cytotoxicity, particularly for covalently functionalized MoS2 nanosheets.
Magnetic Nanoparticle-Mediated Gene Delivery to Neural Stem Cells
The first description on the use of oscillating magnetic fields for magnetic nanoparticle-mediated (MNP) gene transfer to neural stem cells NSCs.