In response to stress, cells must quickly reprogram gene expression to adapt and survive. This is achieved in part by altering levels of mRNAs and their translation into proteins.
Life Science
Cold Plasma To Clean Up Our Water
A team of Canadian researchers has shown that direct contact between an AP “cold” oxidizing plasma source and water that contains very high concentrations of cyanobacteria and green algae, along with associated BMAA toxin, could be quite rapidly (in minutes) decontaminated with modest energy input.
Are Woodpeckers Bullheaded?
A combination of experiments and simulations show how woodpeckers are protected from concussion by the structure of their skull.
Stem Cell-Macrophage Interactions with Ferumoxytol and Ferumoxytol-derived Nanoparticles
“Off the shelf” allogeneic stem cell transplants and stem cell nano‐composites are being used for the treatment of degenerative bone diseases. However, major and minor histocompatibility antigens of therapeutic cell transplants can be recognized as foreign and lead to their rejection by the host immune system.
Memory Allocation in the Hippocampus
Thiago França and José Monserrat discuss how episodic memories are coded by the hippocampus.
Recent Advances of Light-Based Single-Molecule Approaches for Studying Biomolecules
Recent advances in single‐molecule techniques have led to new discoveries in analytical chemistry, biophysics, and medicine. Understanding the structure and behavior of single biomolecules provides a wealth of information compared to studying large ensembles.
Scalable Method to Generate Human iPSC-Derived Macrophages
Protocol for iPSC-derived macrophages with excellent functional and transcriptomic fidelity.
Surviving Phosphate Limitation via the C-P Lyase Pathway
The mechanisms for how bacteria break down phosphonates in order to overcome times of phosphate limitation.
RNAs in the Spliceosome: Insights from CryoEM Structures
Recent high‐resolution cryoEM structures of various spliceosomal complexes reveal unprecedented details of this large molecular machine.
Organotypic Culture System for in vitro Bone Modeling
An organotypic culture system that allows the production of bone tissue features on a centimeter scale.
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