Self-assembling protein nanoparticles that target the mitochondria and rapidly accumulate in tumors have potential for combination therapies.
Life Science
When Multi-Subunit Complexes Meet: Replisome-Cohesin Interactions at the Replication Fork
Exploring cohesin and replisome interactions during DNA replication.
Microtruck Delivery Service: Transporting Microcargo using Amoeboid Cells
Amoeboid cell microtransporters carry microcargo in an independent, self-organized fashion.
Rnt1p: An Alternative to RNAi for Targeted RNA Degradation
The double‐stranded RNA‐binding protein family controls RNA editing, stability, and function in all eukaryotes.
Mimicking Healthy and Diseased Cell Environments
Research suggests that epigenetic remodeling can be persistent and might be a memory keeper.
Systematic Mass Spectrometry‐based Method for Spatial Proteomics
Proteome-wide analysis of protein subcellular localization changes.
Generating and Working with Drosophila Cell Cultures
Challenges and opportunities to improve the state of Drosophila cell cultures.
Modelling the Architecture of the Cell Nucleus
Polymer physics is the basis to models that explain chromatin folding mechanisms.
Emerging Peptide Science in Canada
Peptide research in Canada is highighted in a special issue of Peptide Science, guest edited by William D. Lubell.
Accelerating Drug Discovery for Targeting G Protein-Coupled Receptors
Outstanding structural and pharmacological features of eight unique lipid‐binding receptors, one of the most difficult G protein‐coupled receptor families to study, have been revealed.
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