In their review in BioEssays, David Popp et al. discuss how recent advances in structural biology have provided new insights into biological filament systems.
Life Science
What Goes On in a Stressed Brain?
Important implications for the development of therapeutics, and several potential pharmacological targets for the treatment of stress‐related disorders have been identified.
The Little Ice Age: Climate and Society in the 15th through 18th Centuries
Scholars in different fields have contrasted the fates of societies or communities that were “vulnerable” to climate change with those that seem to have been “resilient” or even consciously or unconsciously adaptive in the face of the Little Ice Age.
Sampling from Single Living Cells
Nanoprobe-based methods can sample the content of a single living cell without affecting its viability.
Genetic Variants in mRNA Untranslated Regions
Discussing the mechanisms of UTR regulation, the role of genetic variants in modulating RNA processing, and protein production in human disease.
Flexible Brain-Machine Interface
High-density stretchable electrode grids based on a material that can resolve high spatiotemporal neural signals from the surface of the cortex in freely moving rats with stable recording quality during 3 months of implantation.
Chloride and Plasma: An Antibacterial Match?
A team of Chinese researchers investigated the plasma-induced inactivation behavior of several bacteria without and with the presence of chloride.
PROTACs: Eliminating Disease-Causing Proteins
PROTACs (proteolysis-targeting chimeric molecules): A review and discussion of the technique and its application to therapies and drug discovery.
Shining a Light on the Nicobar Pigeon
The iridescence of Nicobar pigeon plumage is put under the microscope.
Water in Mountain Ecosystems with a Mediterranean Climate
Predicting and managing resources in a changing climate requires an understanding of plant-accessible subsurface water storage.
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