Limbal stem cells have attracted a lot of interest in the field of regenerative medicine because of their unique ability to fully restore the whole cornea upon transplantation. Several important aspects of limbal stem cell biology are reviewed such as limbal stem cell identification, developmental origin and therapeutic potential.
Life Science
Hearing Crosstalk: The Molecular Conversation Orchestrating Inner Ear Dorsoventral Patterning
Schoenwolf et al. focus on the crosstalk that occurs among three families of secreted proteins to progressively polarize and pattern the developing otocyst dorsoventrally.
Advances in Deciphering the 3D Organization of Genomes
In their review in BioEssays, Sergey Ulianov et al. discuss recent developments in single cell Hi-C techniques for studying 3D chromatin organization.
mRNA Transport in Fungal Top Models
The study of simple fungal model organisms provides valuable insights into fundamental mechanisms of mRNA transport boosting the understanding of similar events in higher eukaryotes.
The “Space Bear” is Weird, but Not That Weird…
Together with many eukaryotes in which relatively large percentages of lateral gene transfer had been claimed, Tardigrades are now downgraded to normality, and here’s why…
Cyclic-di-GMP Regulation of Virulence in Bacterial Pathogens
Cyclic-di-GMP regulation of bacterial virulence is specific to each pathogen, strain, and type of infection. Differences in the composition and structure of extracellular matrix components could underlie the variation in immune response in the mammalian host.
RNA Uridylation: A Key Post-Transcriptional Modification Shaping the Coding and Non-Coding Transcriptome
Uridylation is a widespread post-transcriptional modification impacting the fate of coding and non-coding RNAs in eukaryotes.
Cover Art – Featuring Centrifugal Lithography, Wound Dressings and Biosensors
This week’s Advanced Healthcare Materials covers.
Live–Cell Imaging via a Clickable Probe With an Exceptionally Long Lifetime Shift
–Cells are highly complex and organized entities which are composed of various biological events. Real-time live-cell imaging is important for understanding these physiological processes. However, many existing fluorescent probes are unsuitable for these purposes due...
Most Read – Featuring Miniature Human Organs, Brain Development Models and Neurodegenerative Disorders
This month’s top Advanced Healthcare Materials papers.
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