Stanislav Piletsky and his colleagues have used molecularly imprinted polymer nanoparticles to replace both antibodies and enzymes in biological assays.
Results for "antibodies"
Targeted siRNA Delivery Using Aptamer-siRNA Chimeras and Aptamer-Conjugated Nanoparticles
Recent advances in aptamer-mediated siRNA delivery systems for RNAi therapy ranging from anticancer therapy to antiviral therapy.
From Microbes and Fetal Allografts to a Better Understanding of Cancer Immune Tolerance
In their ‘Think again’ article published in BioEssays, Megan Barnet and colleagues discuss how insights from fetal allografts and microbes can lead to a better understanding of immune tolerance in cancer.
New Ultra‐Low‐Cost Smartphone Sensor To Diagnose Autoimmune Disease
American researchers designed a smartphone octo‐channel optosensor (SOS) for low‐cost low‐volume lab tests as a mHealth diagnostic tool.
Shucks, Shellfish Allergies are Complex
The mechanisms at play in shellfish allergies are put under the grill.
Selective Protein Immobilization without Purification
Protein immobilization directly from cell lysates is demonstrated in a new process that avoids expensive purification steps but expertly maintains target protein selectivity.
Cover Art – Therapeutic Nucleic Acids, Antibody Validation and Human Tissue Models
Latest Advanced Healthcare Materials covers.
Serotonin Neuron Development: Shaping Molecular and Structural Identities
Serotonin neurons are highly plastic; their development, maturation and regeneration is controlled by a complex gene regulatory network in constant interaction with the environment. An overview article recently published in WIREs Developmental Biology offers an updated view of these fundamental developmental mechanisms, pointing to the many ways by which developmental dysfunction of serotonin systems might occur at different periods in life. This opens new possibilities for therapeutic intervention, which can range from prevention of risk to stem cell therapies.
Particle Targeting in Complex Biological Media
Parameters that affect the biological performance of particles and highlight strategies for improved targeting ability of particles.
Measuring Protein-RNA Interactions Inside Living Cells
Methods to capture protein-RNA interactions. Different techniques are required to capture single-stranded (green), double-stranded (blue), and indirect (yellow) RNA interactions. Crosses (X) in red mark RNA sites that are crosslinked to the RNA binding protein.
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