The active structure of an oral macrocyclic drug has eluded scientists for years despite its widespread clinical use—that is, until now.
Hair provides first direct evidence of drug use during the Bronze Age
Analyzing human hair from remains recovered in Menorca, researchers say they have provided the earliest direct evidence of drug use.
Discovery of a natural anti-stress pathway could help anxiety
A pathway in the brain that forms its natural stress response could be used to make new treatments for anxiety.
Novel lung model to test drugs and understand infections
New lung model raises hopes for more realistic modeling of new drugs and therapies.
HIV drug repurposed for memory loss treatment
Researchers identify a protein that stops the brain from connecting memories, and regulating it could help improve memory loss treatment.
Why are antiviral drugs for COVID-19 difficult to find?
Viruses are so varied and evolve so quickly that creating effective treatments against them becomes a daunting task.
“Breast cancer-on-a-chip” helps researchers test immunotherapy drugs
A new microwell chip holds promise for screening immunotherapy drugs with the added bonus that it can include a patient’s own cells for optimized treatment planning.
Nobel Prize in Medicine awarded for the discovery of hepatitis C
This year’s Nobel Prize in Physiology or Medicine recognizes the achievements made in identifying and treating hepatitis C.
Quantum computers will help us explore life, design new drugs, and more
New quantum algorithms will have dramatic impact in computational molecular biology and bioinformatics and promise to impact a number of life science applications.
Conserved elements in viral genomes may provide targets for broad-spectrum drugs
RNA elements that are found in the genomes of numerous representatives within the same virus family provide new opportunities to expand the repertoire of targets for the development of antiviral therapy.