A multifunctional targeting of intracranial glioma inspired by the intoxication mechanism of the Cholera toxin is demonstrated.
Emerging Roles of hnRNPA1 in Modulating Malignant Transformation
hnRNPA1 is involved in multiple biological processes within the cell nucleus and cytoplasm.
What’s the Issue? Biomimetic Interfaces in Biomedical Devices
This week’s Advanced Healthcare Materials special issue with João Mano, Ali Khademhosseini, and Insung Choi.
Using Genome-Scale Metabolic Models for Human Diseases
Genome-scale metabolic models (GEMs) are relatively new tools for studying the metabolic changes associated with many diseases. GEMs are reconstructions of the metabolic networks of cells, sometimes able to represent an organism’s whole body.
Single-Molecule Molecular Machines
Protein Science has published a Special Issue on Molecular Machines guest edited by Carlos Bustamante from the Laboratory of Single Molecule Biophysics at UC Berkeley. Each living cell, whether prokaryotic or eukaryotic, is a microscopic but complex structure. Its...
Algae as a Sustainable Raw Material for Biodiesel Production
A recent Review takes an in-depth look at the current status and future prospects of supercritical transesterification.
Mutantelec: A Simulation Platform for Profiling of Proteins
The electrostatic potential of proteins determines their ability to interact with specific biological targets. A recent article discusses the application of a novel tool (Mutantelec) in understanding mutations in the tumor suppressor protein p53 and its consequence.s
Stem Cell Manufacturing
A hydrogel coating platform for microcarriers based on interfacial polymerization enables scalable production of mesenchymal stem cells.
The Best Models of Metabolism
This Review outlines the metabolic model design process and discusses the numerous choices for modeling frameworks and mathematical representations.
Monoubiquitination: A New Signal for Proteasomal Degradation
In their review in BioEssays, Ido Livneh et al. discuss recent findings that establish monoubiquitination as a proteasomal targeting signal.