An advanced review recently published in WIREs Developmental Biology summarizes insights about the genetic basis of variation of quantitative traits from the many GWA analyses of morphological, behavioral, life history and other traits that have been published to date using the DGRP and populations derived from it.
Results for "DNA"
Measuring Protein-RNA Interactions Inside Living Cells
Methods to capture protein-RNA interactions. Different techniques are required to capture single-stranded (green), double-stranded (blue), and indirect (yellow) RNA interactions. Crosses (X) in red mark RNA sites that are crosslinked to the RNA binding protein.
RNA on the Brain: Emerging Layers of Post-Transcriptional Regulation in Cortical Development
A new review by Lennox et al discuss recent advances in our understanding of post-transcriptional regulation during embryonic cerebral cortex development.
Chromatin-associated non-coding RNAs in development and inheritance
The diverse roles of chromatin-associated non-coding RNAs.
Non-Toxic Targeted Gene Therapy in Obese Rats
Obesity is a growing epidemic around the world.
Nature’s Nanoparticles for Improving Gene Transfer
A cryo-transmission electron micrograph of a new gene delivery system called exo-AAV. The adeno-associated virus vector (AAV) is packaged within a lipid bubble called an exosome. Multiple AAV vectors can be observed as dark structures inside the larger spherical exosome structure.
Crosstalk Between Transcription and Metabolism: How Much Enzyme is Enough for a Cell?
A recent review by Donati, Sander and Link tries to answer this question.
Murray Goodman Memorial Prize Nominations – Deadline Extended
Nominate a colleague for the Biopolymers Murray Goodman Memorial Prize, awarded for accomplishments in biochemistry, biophysical chemistry, biophysics and/or chemical biology.
Genetically-Encoded Iron-Associated Proteins as MRI Reporter
Visualization of cells contributing to disease or cell therapy is critical for the success of regenerative medicine. Genetically encoded iron-associated proteins detectable with magnetic resonance imaging (MRI) can be utilized for cell tracking in the brain, heart, and cancer.
Plant Viral and Bacteriophage Delivery of Nucleic Acid Therapeutics
Different shaped plant viruses and bacteriophages can be used to deliver nucleic acids into the cell for disease treatment
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