Results for "DNA"
Immunity to CRISPR Cas9 and Cas12a Therapeutics

Immunity to CRISPR Cas9 and Cas12a Therapeutics

Genome-editing therapeutics introduce foreign nucleic acids and proteins into the circulation and cells, which can activate the innate, cellular, and humoral immunity in human patients. The key obstacle in translating CRISPR therapeutics to the clinic is hence to identify, diminish, and monitor these immunological risks before adverse immune reactions.

mRNA Transport in Fungal Top Models

mRNA Transport in Fungal Top Models

The study of simple fungal model organisms provides valuable insights into fundamental mechanisms of mRNA transport boosting the understanding of similar events in higher eukaryotes.