In his review published in BioEssays, James Haber takes a look at how the ends of a broken chromosome find a template with which to repair such a double-strand break.
Mix and Match Nanobiosensor Design using Self-Assembled DNA Nanostructures
DNA origami nanobiosensor: The binding of the bioanalyte (left) with the ssDNA-associated bioreceptor (center) on the surface of the DNA origami is transduced as a measurable change in properties (right) that can be recognized and quantified by a detector.
Regulating Gene Expression: DNA Provides a Twist
DNA conformation can regulate gene expression, as discussed by Olga Zaytseva and Leonie Quinn in a review in BioEssays.
DNA Replication Revisited: Single-Molecule Analyses Reveal Its Highly Dynamic Nature
In their review in BioEssays, Karl Duderstadt and colleagues challenge the long-held view that DNA replication follows a single highly reproducible sequence of molecular events.
Stabilization and Denaturation of DNA Origami Nanostructures
The stability of DNA origami under strongly denaturing conditions is investigated.
Cover Art – Featuring DNA Origami, Cardiac Scaffolds and Stem Cells
This week’s Advanced Healthcare Materials cover manuscripts.
Biopolymers Murray Goodman Memorial Prize awarded to Jennifer A. Doudna
The 4th Biopolymers Murray Goodman Memorial Prize was awarded at the 2017 Spring ACS meeting in San Francisco to Jennifer A. Doudna.
Using “DNA Flowers” as Carriers for Protein Delivery
In-situ assembled flower-shaped DNA constructs can be used for an efficient intracellular protein delivery.
New DNA Vaccine Enhances Protection Against Hepatitis C Virus
Researchers develop a highly effective DNA vaccine based on oscillating plasmonic gold nanoparticles for protection against the hepatitis C virus.
Proteins Feel the Pinch with DNA Nanotweezers
In a study published in the new journal Advanced Biosystems, scientists from the University of Hong Kong demonstrated that it is possible to use a DNA aptamer split across a tweezer such that the presence of the target protein triggers the DNA tweezer mechanism.