New directions in which ncRNAs can be exploited in Alzheimer’s disease prevention, diagnosis, prognosis, and therapy are discussed.
Results for "brain"
Generation of Diverse Cortical Inhibitory Interneurons
Our current understanding of the generation of cortical interneurons with a focus on recent efforts to bridge the gap between progenitor behavior and interneuron production is reviewed.
Timing of Neuronal Plasticity in Development and Aging
An overview of the many key pathways and neuronal clocks that have been linked to the regulation of regenerative capacity is provided.
Aneuploidy and Chromosomal Instability: Their Relationship and Consequences
In their review in BioEssays, Klaske Schukken and Floris Foijer discuss the different concepts and consequences of chromosomal instability and aneuploidy.
Asleep or Awake? Deciphering the Molecular Mechanisms of Sleep Regulation
In their review in BioEssays, Shoi Shi and Hiroki Ueda review recent studies on sleep duration and homeostasis.
Cover Art – Nanoparticle Delivery, Implants, Cell Culture Platforms and Microscaffolds
Latest Advanced Healthcare Materials covers.
Most Read in Biomedicine–Wound Healing, Nerve Guide Conduits, Organ-on-Chip, and More
Advanced Healthcare Materials papers you have downloaded and read the most in the past two months.
Confererence Report: TEDx Berlin
This year’s edition of TEDx Berlin, entitled “FOCUS”, was held on September 3rd and encompassed three sessions with invited speakers in different topics covering Digital Life and its challenges. Image copyright TEDxBerlin 2017.
Serotonin Neuron Development: Shaping Molecular and Structural Identities
Serotonin neurons are highly plastic; their development, maturation and regeneration is controlled by a complex gene regulatory network in constant interaction with the environment. An overview article recently published in WIREs Developmental Biology offers an updated view of these fundamental developmental mechanisms, pointing to the many ways by which developmental dysfunction of serotonin systems might occur at different periods in life. This opens new possibilities for therapeutic intervention, which can range from prevention of risk to stem cell therapies.
Hearing Crosstalk: The Molecular Conversation Orchestrating Inner Ear Dorsoventral Patterning
Schoenwolf et al. focus on the crosstalk that occurs among three families of secreted proteins to progressively polarize and pattern the developing otocyst dorsoventrally.
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