The potential of rapid diagnostics and screening has led to burgeoning interest in droplets, as it is increasingly used to detect novel disease biomarker targets.
New Simple Biomarker Imaging Technique for Critical Diseases
A simple optical imaging technique for biomarker analysis for critical diseases.
Cover Art – Theranostics, Pre-Metastatic Niche and Bone Regeneration
Check out the latest covers of Advanced Healthcare Materials!
CRISPR-based Genome Editing via Non-Viral Delivery
This non-viral CRISPR-Cas9 delivery vector is ten times as effective at genome modification as the standard plasmid transfection techniques, down-regulating Plk1 expression over 70% to inhibit tumor growth.
Lasering in on Retinoblastoma
A technique using gold nanoparticles and laser pulses can successfully destroy retinoblastoma cells.
Targeting RNA in Mammalian Systems with Small Molecules
Small molecules have been used to study several mammalian RNA elements in disease. These advances encourage exploration of newly discovered RNA interactions with therapeutic potential.
LARP1 on TOP of Ribosome Production
Ribosome production is a considerable energy investment for the cell—rRNAs and ribosomal proteins (RPs) are among the most abundant classes of RNAs and proteins—and their production must, therefore, be synchronized temporally and stoichiometrically to ensure efficient ribosome assembly.
Switch the Photosensitizer On!
A strategy to transform various photosensitizers into activatable ones for photodynamic therapy is reported.
Cover Art – Microrobots for Cell & Drug Delivery and Synthetic Cells
Check out the latest covers of Advanced Healthcare Materials!
BET Proteins and Nrf2: Studying their Interplay May Offer New Therapeutic Opportunities
In their “Hypothesis” article published in BioEssays, Nirmalya Chatterjee and Dirk Bohmann discuss the interplay between Nrf2 and BET proteins and the resultant implications for therapies targeting these proteins.