Marcelo Calderón and co-workers report on the design of a responsive nanogel system for a combined photothermal and photodynamic therapy of cancer. Based on a radical precipitation method, the near infrared absorbing cyanine green dye IR806 was conjugated to the macro crosslinker polyglycerol and polymerized into a thermoresponsive polyether based nanogel network.
Reviews Special Issue in Molecular Nutrition & Food Research
Check out the covers and top articles of the Reviews Special Issue in Molecular Nutrition & Food Research.
New special issue in Small celebrates 10 years of research at SINANO
A new special issue in Small this month highlights 10 years of fundamental and applied research at SINANO.
Stability in Polymeric Micelles – Make it a Better Nanomedicine
A recently published feature article discusses the reasons for the poor targeting efficiency via polymeric micelles, and the approaches that have been explored to tackle this problem.
MicroRNA-Responsive Drug Release System for Selective Photodynamic Therapy
A microRNA-responsive drug release system will strengthen the selectiveness of the photodynamic therapy system.
A new near-infrared responsive drug carrier for imaging-guided chemotherapy
A promising multifunctional nanocarrier for opto-acoustic imaging-guided chemotherapy or phtotothermal therapy is presented.
Protein cages for drug delivery
Researchers linked a polymeric transfection reagent into a hollow protein nanocage for drug delivery.
Lighting up enzymatic drug release by FRET
A new generation of enzyme-responsive HPMA copolymer-drug conjugates employing a enzyme-sensitive oligopeptide linker was developed. Fluorescence resonance energy transfer (FRET) was applied to investigate the enzyme-responsive performance in both cells and animals.
Watching apoptosis in 3D
A promising approach for watching cell signaling processes in their physiological context.
Carbon-dot nanosystem for photodynamic therapy
A carbon-dot nanosystem is developed for photodynamic therapy, which releases a photosensitizer bioprecursor in cancer cells upon irradiation.