Results for "cancer"
Nanogels for photothermal and photodynamic therapy

Nanogels for photothermal and photodynamic therapy

Marcelo Calderón and co-workers report on the design of a responsive nanogel system for a combined photothermal and photodynamic therapy of cancer. Based on a radical precipitation method, the near infrared absorbing cyanine green dye IR806 was conjugated to the macro crosslinker polyglycerol and polymerized into a thermoresponsive polyether based nanogel network.

Lighting up enzymatic drug release by FRET

Lighting up enzymatic drug release by FRET

A new generation of enzyme-responsive HPMA copolymer-drug conjugates employing a enzyme-sensitive oligopeptide linker was developed. Fluorescence resonance energy transfer (FRET) was applied to investigate the enzyme-responsive performance in both cells and animals.