Low cost, on-chip, high-resolution imaging to study cellular dymamics of intact brain organoids.

Low cost, on-chip, high-resolution imaging to study cellular dymamics of intact brain organoids.
In her article published in BioEssays, Nora Engel discusses how sex differences become established in early embryogenesis and how analyzing the underlying mechanisms can lead to a better understanding of sex differences in health and disease.
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Knowledge of the processes needed to make precursor cells of eggs and sperm gives insights into reproductive biology and infertility.
Sequencing of the human genome led to the surprising discovery that we do not have many more protein coding genes than presumably simpler organisms.
The key players within the pathways of RNA decay are well conserved with their mutation or disruption resulting in distinct phenotypes as well as human disease.
An investigation into how pioneer factors interact with closed chromatin to influence chromatin landscapes and generate differentiated cells.
In their review published in BioEssays, Sandra Richardson and Geoffrey Faulkner discuss the origins and implications of L1 retrotransposition events during development.
n their review published in BioEssays, Mahesh Sangrithi and James Turner discuss mammalian X chromosome dosage compensation with a particular focus on the germ line.
Bioactive entities are combined into structurally ordered multidomain protein complexes to mitigate selective targeting of a hallmark protein molecule in cancer diseases.