Throughout development and into adulthood, Wnt proteins ensure embryonic patterning, cellular proliferation, cellular identity, and organization of tissues.
How Did the Complex Nervous Systems of Animals Evolve?
Genomics, and molecular and cellular biology have recently revealed fundamental similarities between embryonic nervous system development in echinoderms and vertebrate neural development, suggesting a common origin for the nervous systems of all animals.
Laser Spectroscopy Diagnoses Freshness and Fertilization of Hen Egg
A team of Chinese researchers used a GASMAS optical spectroscopy technique to study the degree of freshness of unfertilized eggs and to distinguish unfertilized eggs from fertilized eggs.
Serotonin Neuron Development: Shaping Molecular and Structural Identities
Serotonin neurons are highly plastic; their development, maturation and regeneration is controlled by a complex gene regulatory network in constant interaction with the environment. An overview article recently published in WIREs Developmental Biology offers an updated view of these fundamental developmental mechanisms, pointing to the many ways by which developmental dysfunction of serotonin systems might occur at different periods in life. This opens new possibilities for therapeutic intervention, which can range from prevention of risk to stem cell therapies.
Hearing Crosstalk: The Molecular Conversation Orchestrating Inner Ear Dorsoventral Patterning
Schoenwolf et al. focus on the crosstalk that occurs among three families of secreted proteins to progressively polarize and pattern the developing otocyst dorsoventrally.
Regulation of Germ Cell Development by Intercellular Signaling in the Mammalian Ovarian Follicle
Unlike all other cells in the body, which age and eventually die, a female’s oocytes can give rise to a new individual. Oocytes have, in a sense, achieved immortality. In order to reach this exalted state, each oocyte undergoes a complex program of differentiation within the ovary before it is ovulated and fertilized.
Rainbow Cell Barcoding: Fluorescent Polymer Nanoparticles
A method that allows the long-term labeling of different cell populations in tens of different colors using fluorescent nanoparticles.
RNA on the Brain: Emerging Layers of Post-Transcriptional Regulation in Cortical Development
A new review by Lennox et al discuss recent advances in our understanding of post-transcriptional regulation during embryonic cerebral cortex development.
Segmental Arithmetic: Summing Up the Hox Gene Regulatory Network for Hindbrain Development in Chordates
It is important to understand when and how the hindbrain segmentation program evolved. Recent studies have shed some light.
Biomimetic Apatite Formation
There is a growing body of evidence that a secondary structure of highly negatively charged proteins can play an important role in localizing calcium and phosphate ions to promote the formation of the HAp deposits.