Cell fate and dynamic behavior of cells can easily be monitored in microfluidics using few cells and reagents for regenerative medicine applications.
Results for "embryo"
Understanding Mouth Development
The mouth is essential for eating and has ancient origins. A new review looks at the evolution of the mouth and insights into the vertebrate mouth opening from the frog Xenopus laevis.
Electrophysiological Analysis of Synaptic Transmission in Drosophila
An overview of how synaptic transmission is assayed in the Drosophila neuromuscular and central nervous systems.
Shiny New Scissors in the CRISPR/Cas9 Toolbox for Advanced Genome Editing
The CRISPR/Cas9 toolbox has been expanded with fluorescent Cas9 and a dCas9 functionalized with a tag able to activate gene expression that can be transfected to cells directly as ribonucleoprotein complexes (RNP).
Same Signal, Different Tissues: Morphogen Interpretation
How developmental cues specify these distinct cell types in embryos and coordinate their patterning into functional tissues is one of the fundamental questions of developmental biology.
Functional microRNA Screen for Organ Morphogenesis
A detailed protocol to assess microRNA function in explanted organs is presented.
A High-Throughput Cell Chemotaxis and Migration Inhibitor Screen
A protocol for a unique high-throughput assay to identify novel small-molecule inhibitors of cell migration.
Does Nicotine Affect “Recycling” of Cellular Components?
Using a proteomics approach, Drs. Paulo and Gygi from the Harvard Medical School provide evidence that nicotine exposure changes the abundance of membrane proteins implicated in signal transduction and autophagy.
Nanofibers for Regenerative Medicine
Researchers study new bioactive scaffolds based on PLA fibers, modified with a peptide sequence derived from fibronectin, an extracellular matrix component.
Fluorescence microscopy research wins 2014 Nobel Prize in Chemistry
Eric Betzig, Howard Hughes Medical Institute, Stefan Hell, Max Planck Institute for Biophysical Chemistry, and William Moerner, Stanford University, share award for the development of super-resolved fluorescence microscopy.
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