High-Throughput in situ Synthesis of Biomimetic Magnetite Loaded Nanovesicles Naturally occurring magnetite magnetic nanoparticles are produced by magnetic bacteria within liposomes called magnetosomes. These have numerous desirable properties, for example, they are...
Anisotropic Scaffold for the Regeneration of Osteochondral Defects
A methacrylated hyaluronic acid scaffold with oriented pores perpendicular to the axial direction by an unidirectional freeze-drying method is reported.
Polyphosphoesters: new trends in synthesis and drug delivery
Polyphosphoesters, with their unique features and diverse functionalities, hold tremendous potential to advance drugs carriers. Advanced synthetic tools to synthesize them efficiently and functionalization methodologies are discussed
Tackling challenges in siRNA delivery with designed oligoamides
In their recent review in Macromolecular Bioscience, Sören Reinhard and Ernst Wagner deal with the challenges in siRNA delivery and how they can be overcome.
Biosensing with Polymer-Graphene Nanocomposites
So-called “biosensors” are sensors that detect or quantify biomolecules, such as glucose, proteins, or DNA.
Stability in Polymeric Micelles – Make it a Better Nanomedicine
A recently published feature article discusses the reasons for the poor targeting efficiency via polymeric micelles, and the approaches that have been explored to tackle this problem.
Reducing Adsorption of Proteins on Nanoparticles
To avoid an undesired protein adsorption, nanoparticles were masked with poly(2-oxazoline)s resulting in a stealth coating comparable or superior to PEG.
Conductive Polymeric Biomaterials
Different mechanisms for imparting conductivity to non-conductive polymeric biomaterials are discussed in a review by Patton et. al.
Lighting up enzymatic drug release by FRET
A new generation of enzyme-responsive HPMA copolymer-drug conjugates employing a enzyme-sensitive oligopeptide linker was developed. Fluorescence resonance energy transfer (FRET) was applied to investigate the enzyme-responsive performance in both cells and animals.
Tailoring degradation in polymeric nanogels
To tailor the degradation of nanogels, Scientists from Utrecht University investigated the impact of the structure of polymeric building blocks on the properties of nanogels and their degradation behavior.