Genome-editing therapeutics introduce foreign nucleic acids and proteins into the circulation and cells, which can activate the innate, cellular, and humoral immunity in human patients. The key obstacle in translating CRISPR therapeutics to the clinic is hence to identify, diminish, and monitor these immunological risks before adverse immune reactions.
Confererence Report: TEDx Berlin
This year’s edition of TEDx Berlin, entitled “FOCUS”, was held on September 3rd and encompassed three sessions with invited speakers in different topics covering Digital Life and its challenges. Image copyright TEDxBerlin 2017.
Multiscale Memory and Bioelectric Error Correction in the Cytoplasm-Cytoskeleton-Membrane System
Pattern regulation, as observed in regeneration and development, enables cells to cooperate toward the creation and maintenance of complex anatomies. This image shows planaria, of which every piece has the information needed to restore a complete planarian target morphology.
A Bright Future For InGaN Photonic Crystal Light Emitters
Via a bottom-up approach this research shows the production of scalable, stable InGaN nanowire photonic crystals for high efficient LEDs.
Atomic Force Microscopy Captures the Liquid/Liquid Interface
Stabilizing interfacial layers enable atomic force microscopy imaging of soft and dynamic liquid/liquid interfaces without any solid support.
Lemon-based Bio-Plastics
Spanish researcher found a way to replace bisphenol-A with limonene in polycarbonates.
Ascidians: Our Closest Invertebrate Relatives?
Recent knowledge about metamorphosis and adult organ formation of ascidians is reviewed, in order to elucidate the molecular similarities with those in vertebrates.
Limbal Stem Cells for Treatment of Corneal Blindness
Limbal stem cells have attracted a lot of interest in the field of regenerative medicine because of their unique ability to fully restore the whole cornea upon transplantation. Several important aspects of limbal stem cell biology are reviewed such as limbal stem cell identification, developmental origin and therapeutic potential.
Citizen Science for Hydrological Risk Reduction and Resilience Building
Citizen science projects work best when there is community buy-in, when their purposes are clearly defined at the outset, and when the motivations and skill-sets of all participants and stakeholders are well understood.
Biopolymers Murray Goodman Memorial Prize Winner 2017: William F. DeGrado
Recognizing his seminal contributions to the de novo design of peptides, proteins and pharmaceutically-active small molecules, we are thrilled to present Professor William F. DeGrado with the 2017 Biopolymers Murray Goodman Memorial Prize.