Nanocarriers can be precision-engineered to capitalize on what is known about receptor expression patterns, receptor clustering, and ultimately how interactions between a nanocarrier and target can be manipulated to achieve the most effective downstream signaling events.
Biomaterials are engineered to improve the safety and efficacy of current cancer immunotherapies.
Nanostructured hydroxyapatite (nHAp) appears to have a great potential to revolutionize the hard tissue-engineering field, starting from bone repair and augmentation to controlled drug delivery systems.
In contrast to healthy tissue, tumors demand a high supply of nutrients and oxygen, and will invade existing vessels and develop new ones to meet these demands.
A biomolecular adsorption layer (corona) forms on essentially all nanoparticles immersed in biological fluids, and governs their interactions with the biological environment. Key aspects of protein corona formation and its structure and dynamics have yet remained elusive and call for further investigations.
Drug nanocrystals deliver drugs via oral, intravenous, and local administration and show promise towards treating cancer more effectively.
Pulmonary exposure to carbon nanotubes can result in direct interaction with cells in the lung and result in an increased myofibroblast population thereby enhancing fibrogenesis, the severity of which is determined by physicochemical characteristics of the nanotubes and genetic susceptibility.
Biodegradable synthetic poly(Amino Acid) carrying either therapeutic or diagnostic agents.
A vast number of metallic and non-metallic labels can be conjugated to the dendrimer surface in order to transform them into MRI agents. Due to their multiple branches and high payload they can be readily detected, for example, following local delivery to a brain tumor.
A cryo-transmission electron micrograph of a new gene delivery system called exo-AAV. The adeno-associated virus vector (AAV) is packaged within a lipid bubble called an exosome. Multiple AAV vectors can be observed as dark structures inside the larger spherical exosome structure.
Quantum entanglement visualized for the first time ever
Tiny robots with a big impact: Scientists develop microrobots for single-cell handling
An anti-inflammatory peptide may hold the key to low-back pain relief
String theory provides a new take on the expansion of the Universe
Cutting out processed foods doesn’t automatically make a diet healthier
How the brain protects itself from the negative effects of CBD
Gliese 12 b: An exo-Venus with Earth-like temperatures
Could a nuclear explosion set Earth’s atmosphere on fire?
New study reveals surprising impact of screen time on the developing brain
Contact lenses bring 3D holograms to life for augmented reality