Large-scale recoding of virus genomes has the potential for use in vaccine design.
WIREs RNA
Protein synthesis: An adaptive “hive mind” of cellular proportions
New evidence suggests a hidden “intelligence” of a life-sustaining pathway.
Where and how do RNAs localize in tiny prokaryotic cells?
Similar to eukaryotes, prokaryotic cells can spatiotemporally regulate localization of RNAs, which is crucial for the survival and proper function of these tiny organisms.
When viruses borrow artillery
Researchers explore the different mechanisms viruses have evolved to effectively seize host cell ribosomes, and the role they play in the virus’ life cycle.
RNA-RNA interfaces as a possible antibiotic target
RNA “sandwiches” perform crucial roles in a range of bacterial metabolic pathways.
The route of all COVID-19 evil: RNA
RNA-related processes that are key to the biology of the cell are at risk during coronavirus infections.
Imaging the life cycle of RNA
RNA plays a fundamental role in our health and biology, and advancements in imaging techniques are expanding our understanding of its life cycle.
Conserved elements in viral genomes may provide targets for broad-spectrum drugs
RNA elements that are found in the genomes of numerous representatives within the same virus family provide new opportunities to expand the repertoire of targets for the development of antiviral therapy.
Targeting the untargetable and treating the untreatable
A blackboard of therapeutic innovation: Researchers seek to understand how antisense oligonucleotides can “erase” disorders.
Business as usual … on the edge: Neuronal outgrowths do their own maintenance
Understanding how mRNA localization changes during healthy brain functions and pathological conditions.
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