Chimeric RNAs can be generated by not only chromosomal rearrangements at the DNA level, but also intergenic splicing at the RNA level. Chimeric RNAs are demonstrated to be not the elusive features of cancer cells, but also present in normal physiology and with diverse functions.
Organelle-localized RNA recognition motif-containing proteins participate in a variety of RNA-related processes, including RNA editing, RNA processing, and RNA stability.
Do not expect RNA to sit still. Although structural investigations typically illustrate a single, more or less static picture of an RNA, most RNAs most undergo conformational changes to exert their cellular function.
Microexon regulation has the ability to modulate protein properties, including mechanistic links to diseases like autism.
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